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DNER Antibody(C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - DNER Antibody(C-term) AP19467b
    DNER Antibody (C-term) (Cat. #AP19467b) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the DNER antibody detected the DNER protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8NFT8
Other Accession Q8JZM4, NP_620711.3
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 78475 Da
Antigen Region 708-736 aa
Additional Information
Gene ID 92737
Other Names Delta and Notch-like epidermal growth factor-related receptor, DNER, BET
Target/Specificity This DNER antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 708-736 amino acids from the C-terminal region of human DNER.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDNER Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DNER
Synonyms BET
Function Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein. Note=Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).
Tissue Location Expressed in brain, spinal cord and adrenal gland.
Research Areas
Citations (0)
citation

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Background

Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity).

References

Kurisu, J., et al. J. Neurochem. 113(6):1598-1610(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Park, J.R., et al. Cell Prolif. 43(1):19-28(2010)
Ramachandran, P., et al. J. Proteome Res. 5(6):1493-1503(2006)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)

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$ 182.50
$ 70.00
Cat# AP19467b
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