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AGTR1 Antibody (C-term Y319)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - AGTR1 Antibody (C-term Y319) AP20429b
    AGTR1 Antibody (Y319) (Cat.# AP20429b) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the AGTR1 antibody detected the AGTR1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P30556
Other Accession P25095, P29754, P34976, P30555, P25104, O77590
Reactivity Human
Predicted Bovine, Pig, Rabbit, Sheep, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 41061 Da
Antigen Region 297-326 aa
Additional Information
Gene ID 185
Other Names Type-1 angiotensin II receptor, AT1AR, AT1BR, Angiotensin II type-1 receptor, AT1, AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B
Target/Specificity This AGTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-326 amino acids from the C-terminal region of human AGTR1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAGTR1 Antibody (C-term Y319) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGTR1 (HGNC:336)
Function Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney (PubMed:1567413, PubMed:8987975, PubMed:15611106, PubMed:25913193, PubMed:26420482, PubMed:30639100, PubMed:32079768). The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C (PubMed:15611106).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Liver, lung, adrenal and adrenocortical adenomas.
Research Areas
Citations (0)
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Background

Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

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$ 365.00
$ 140.00
Cat# AP20429b
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