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DHX8 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q14562 |
| Other Accession | A2A4P0 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 139315 Da |
| Gene ID | 1659 |
|---|---|
| Other Names | ATP-dependent RNA helicase DHX8, DEAH box protein 8, RNA helicase HRH1, DHX8, DDX8 |
| Target/Specificity | This DHX8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 339-373 amino acids from the N-terminal region of human DHX8. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DHX8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DHX8 |
|---|---|
| Synonyms | DDX8 |
| Function | Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28076346). Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome (PubMed:8608946). |
| Cellular Location | Nucleus |
| Tissue Location | Expressed in skin, cervix and nerve. Also expressed in the brain. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
References
Ono Y.,et al.Mol. Cell. Biol. 14:7611-7620(1994).
Ohno M.,et al.Genes Dev. 10:997-1007(1996).
Jurica M.S.,et al.RNA 8:426-439(2002).
Neuhaus E.M.,et al.J. Cell Sci. 119:3047-3056(2006).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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