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PAR4 (Cleaved-Gly48) Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PAR4 (Cleaved-Gly48) Antibody AP50631
    Western blot analysis of lysates from HepG2,Jurkat cell line (from left to right),using PAR4 (Cleaved-Gly48) Antibody(AP50631). AP50631 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q96RI0
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 41 KDa
Antigen Region 40-68 aa
Additional Information
Gene ID 9002
Other Names Proteinase-activated receptor 4, PAR-4, Coagulation factor II receptor-like 3, Thrombin receptor-like 3, F2RL3, PAR4
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name F2RL3
Synonyms PAR4
Function Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis (PubMed:10079109). May play a role in platelets activation (PubMed:10079109).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets
Research Areas
Citations (0)
citation

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Background

Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.

References

Kahn M.L.,et al.J. Biol. Chem. 273:23290-23296(1998).
Kahn M.L.,et al.Nature 394:690-694(1998).
Xu W.-F.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:6642-6646(1998).
King M.M.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Kahn M.L.,et al.J. Clin. Invest. 103:879-887(1999).

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$ 350.00
Cat# AP50631
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Availability: 2 weeks
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