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CD158g Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CD158g Antibody AP51784
    Anti-CD158g Antibodyat 1:1000 dilution + Hela whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 34 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q14953
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 34 KDa
Antigen Region 141 - 200 aa
Additional Information
Gene ID 3810
Other Names Killer cell immunoglobulin-like receptor 2DS5, CD158 antigen-like family member G, MHC class I NK cell receptor, Natural killer-associated transcript 9, NKAT-9, CD158g, KIR2DS5, CD158G, NKAT9
Target/Specificity KLH conjugated synthetic peptide derived from human CD158g
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name KIR2DS5 {ECO:0000303|PubMed:18624290, ECO:0000312|HGNC:HGNC:6337}
Function Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity (PubMed:28685972, PubMed:18624290, PubMed:18682925). Able to activate NK cells citotoxicity and cytokine production such as IFNG (PubMed:18624290, PubMed:24269691). Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 represented in this entry (PubMed:28685972).
Cellular Location Cell membrane; Single-pass type I membrane protein; Extracellular side
Tissue Location Expressed on a discrete subset of peripheral blood NK cells.
Research Areas
Citations (0)
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Background

Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.

References

Doehring C.,et al.Immunogenetics 44:227-230(1996).

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$ 350.00
Cat# AP51784
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