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Aldehyde dehydrogenase 10 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • WB - Aldehyde dehydrogenase 10 Antibody AP52746
    Western blot detection of Aldehyde dehydrogenase 10 in A549,U251 and HepG2 cell lysates using Aldehyde dehydrogenase 10 mouse mAb (1:1000 diluted).Predicted band size:55KDa.Observed band size:55KDa.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P51648
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Calculated MW 55 KDa
Additional Information
Gene ID 224
Other Names Aldehyde dehydrogenase;Aldehyde dehydrogenase 10;Aldehyde dehydrogenase 3 family member A2;ALDH10;ALDH3A2;DKFZp686E23276;FALDH;Fatty aldehyde dehydrogenase;FLJ20851;Microsomal aldehyde dehydrogenase;OTTHUMP00000065799;OTTHUMP00000065800;OTTHUMP00000065801;SLS.
Dilution WB~~1:1000
Format Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.09% (W/V) sodium azide, 50%,glycerol
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name ALDH3A2
Function Catalyzes the oxidation of medium and long chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length (PubMed:9133646, PubMed:22633490, PubMed:25047030, PubMed:18035827, PubMed:9662422, PubMed:18182499). Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid (PubMed:22633490).
Cellular Location Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side {ECO:0000250|UniProtKB:P30839}
Tissue Location Detected in liver (at protein level).
Research Areas
Citations (0)
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Background

Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid.

References

de Laurenzi V.,et al.Nat. Genet. 12:52-57(1996).
Rogers G.R.,et al.Genomics 39:127-135(1997).
Chang C.,et al.Genomics 40:80-85(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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$ 360.00
Cat# AP52746
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