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FOXE3 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FOXE3 Antibody AP53299
    All lanes : Anti-FOXE3 Antibody at 1:1000 dilution Lane 1: HepG2 whole cell lysate Lane 2: A549 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution. Predicted band size : 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q13461
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 33 KDa
Antigen Region 86-125aa
Additional Information
Gene ID 2301
Other Names Forkhead box protein E3, Forkhead-related protein FKHL12, Forkhead-related transcription factor 8, FREAC-8, FOXE3, FKHL12, FREAC8
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name FOXE3
Synonyms FKHL12, FREAC8
Function Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle (PubMed:22527307, PubMed:25504734). During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation (By similarity). Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm (By similarity). Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye (PubMed:27218149).
Cellular Location Nucleus.
Citations (0)
citation

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References

Carlsson P.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
Semina E.V.,et al.Hum. Mol. Genet. 10:231-236(2001).
Gregory S.G.,et al.Nature 441:315-321(2006).
Larsson C.,et al.Genomics 30:464-469(1995).
Valleix S.,et al.Am. J. Hum. Genet. 79:358-364(2006).

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$ 350.00
Cat# AP53299
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