GAL Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, WB, IF, E |
---|---|
Primary Accession | P22466 |
Other Accession | NP_057057 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 13302 Da |
Antigen Region | 73-101 aa |
Gene ID | 51083 |
---|---|
Other Names | Galanin peptides, Galanin, Galanin message-associated peptide, GMAP, GAL, GAL1, GALN, GLNN |
Target/Specificity | This GAL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-101 amino acids from the C-terminal region of human GAL. |
Dilution | IF~~1:10~50 WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GAL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GAL |
---|---|
Synonyms | GAL1, GALN, GLNN |
Function | Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion. |
Cellular Location | Secreted |
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Provided below are standard protocols that you may find useful for product applications.
Background
Galanin is small neuropeptide that functions as a cellular messenger within the central and peripheral nervous systems, modulating diverse physiologic functions (Mechenthaler, 2008 [PubMed 18500643]).
References
Unschuld, P.G., et al. Neuropsychopharmacology (2010)
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009)
Sugimoto, T., et al. Genes Chromosomes Cancer 48(2):132-142(2009)
Burleigh, D.E., et al. Neuropeptides 16(2):77-82(1990)
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