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GAL Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • IF - GAL Antibody (C-term) AP5746b
    Confocal immunofluorescent analysis of GAL Antibody (C-term)(Cat#AP5746b) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
    detail
  • WB - GAL Antibody (C-term) AP5746b
    GAL Antibody (C-term) (Cat. #AP5746b) western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the GAL antibody detected GAL protein (arrow).
    detail
  • FC - GAL Antibody (C-term) AP5746b
    GAL Antibody (C-term) (Cat. #AP5746b) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, WB, IF, E
Primary Accession P22466
Other Accession NP_057057
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 13302 Da
Antigen Region 73-101 aa
Additional Information
Gene ID 51083
Other Names Galanin peptides, Galanin, Galanin message-associated peptide, GMAP, GAL, GAL1, GALN, GLNN
Target/Specificity This GAL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-101 amino acids from the C-terminal region of human GAL.
Dilution IF~~1:10~50
WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGAL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GAL
Synonyms GAL1, GALN, GLNN
Function Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.
Cellular Location Secreted
Research Areas
Citations (0)
citation

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Background

Galanin is small neuropeptide that functions as a cellular messenger within the central and peripheral nervous systems, modulating diverse physiologic functions (Mechenthaler, 2008 [PubMed 18500643]).

References

Unschuld, P.G., et al. Neuropsychopharmacology (2010)
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009)
Sugimoto, T., et al. Genes Chromosomes Cancer 48(2):132-142(2009)
Burleigh, D.E., et al. Neuropeptides 16(2):77-82(1990)

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$ 365.00
$ 140.00
Cat# AP5746b
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