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CA3 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CA3 Antibody (N-term) AP7633a
    Western blot analysis of CA3 antibody (N-term)(Cat.#AP7633a) in HepG2 cell line lysates (35ug/lane). CA3 (arrow) was detected using the purified Pab.
    detail
  • WB - CA3 Antibody (N-term) AP7633a
    Western blot analysis of CA3 antibody (N-term)(Cat.#AP7633a) in mouse kidney tissue lysates (35ug/lane). CA3 (arrow) was detected using the purified Pab.
    detail
  • SPECIFICATION
  • CITATIONS: 1
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P07451
Other Accession P14141
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 29557 Da
Antigen Region 17-46 aa
Additional Information
Gene ID 761
Other Names Carbonic anhydrase 3, Carbonate dehydratase III, Carbonic anhydrase III, CA-III, CA3
Target/Specificity This CA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human CA3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCA3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CA3 {ECO:0000303|PubMed:9651514, ECO:0000312|HGNC:HGNC:1374}
Function Reversible hydration of carbon dioxide.
Cellular Location Cytoplasm.
Tissue Location Muscle specific.
Research Areas
Citations ( 0 )

Background

Carbonic anhydrase III (CAIII) is a member of carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal.

References

Du,A.L., Autoimmunity 42 (3), 209-215 (2009)
Dai,H.Y., Mol. Carcinog. 47 (12), 956-963 (2008)
Gailly,P., Kidney Int. 74 (1), 52-61 (2008)

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$ 182.50
$ 70.00
Cat# AP7633a
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