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> home > Products > Primary Antibodies > Antibody Collections > Catalog Updated > RPGRIP1 Antibody (Center)
RPGRIP1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- CITATIONS
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- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q96KN7 |
| Other Accession | NP_065099 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 146682 Da |
| Antigen Region | 530-557 aa |
| Gene ID | 57096 |
|---|---|
| Other Names | X-linked retinitis pigmentosa GTPase regulator-interacting protein 1, RPGR-interacting protein 1, RPGRIP1 |
| Target/Specificity | This RPGRIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-557 amino acids from the Central region of human RPGRIP1. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RPGRIP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RPGRIP1 |
|---|---|
| Function | May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells. |
| Cellular Location | Cell projection, cilium. Note=Situated between the axonemal microtubules and the plasma membrane (By similarity). In the retinal photoreceptor cell layer, localizes at the connecting cilium, a thin bridge linking the cell body and the light-sensing outer segment (By similarity). Colocalizes with RGPR in the photoreceptor connecting cilium (By similarity). {ECO:0000250|UniProtKB:Q9EPQ2} |
| Tissue Location | Strong expression in retina, with weaker expression in testis. Expressed in other neurons such as amacrine cells Colocalizes with RGPR in the outer segment of rod photoreceptors and cone outer segments. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
RPGRIP1 is a photoreceptor protein that interacts with retinitis pigmentosa GTPase regulator protein and is a key component of cone and rod photoreceptor cells.
References
Arts,H.H.,et.al., Nat. Genet. 39 (7), 882-888 (2007)
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$ 365.00
$ 140.00
Cat# AP8871c
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