BEST2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q8NFU1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 57139 Da |
Antigen Region | 374-403 aa |
Gene ID | 54831 |
---|---|
Other Names | Bestrophin-2, Vitelliform macular dystrophy 2-like protein 1, BEST2, VMD2L1 |
Target/Specificity | This BEST2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 amino acids from the C-terminal region of human BEST2. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | BEST2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BEST2 |
---|---|
Synonyms | VMD2L1 |
Function | Forms calcium-sensitive chloride channels. Permeable to bicarbonate. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Mainly confined to the retinal pigment epithelium and colon. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
BEST2 is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif.
References
Zhang,Y., et.al, Mol. Vis. 16, 200-206 (2010)
Marsey,L.L. et.al, J. Physiol. (Lond.) 587 (PT 10), 2211-2224 (2009)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.