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GFPT2 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GFPT2 Antibody (Center) AP9282c
    Western blot analysis of GFPT2 Antibody (Center) (Cat. #AP9282c) in A2058, K562 cell line lysates (35ug/lane). GFPT2 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - GFPT2 Antibody (Center) AP9282c
    GFPT2 Antibody (Center) (Cat. #AP9282c) IHC analysis in formalin fixed and paraffin embedded human skin followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GFPT2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • FC - GFPT2 Antibody (Center) AP9282c
    GFPT2 Antibody (Center) (Cat. #AP9282c) flow cytometric analysis of A2058 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, IHC-P, WB, E
Primary Accession O94808
Other Accession Q4KMC4, Q9Z2Z9, Q08DQ2
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 76931 Da
Antigen Region 175-201 aa
Additional Information
Gene ID 9945
Other Names Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2, D-fructose-6-phosphate amidotransferase 2, Glutamine:fructose-6-phosphate amidotransferase 2, GFAT 2, GFAT2, Hexosephosphate aminotransferase 2, GFPT2
Target/Specificity This GFPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-201 amino acids from the Central region of human GFPT2.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGFPT2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GFPT2
Function Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.
Tissue Location Highest levels of expression in heart, placenta, and spinal cord
Research Areas
Citations (0)
citation

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Background

GFPT2 controls the flux of glucose into the hexosamine pathway. This protein most likely involved in regulating the availability of precursors for N-and O-linked glycosylation of proteins.

References

Edwards,T.L., et.al., Ann. Hum. Genet. 74 (2), 97-109 (2010)
Prasad,P., et.al., BMC Med. Genet. 11, 52 (2010)
Srinivasan,V., et.al., Clin. Biochem. 40 (13-14), 952-957 (2007)

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$ 365.00
$ 140.00
Cat# AP9282c
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