SH3BGRL3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q9H299 |
Other Accession | Q3ZCL8 |
Reactivity | Human |
Predicted | Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 10438 Da |
Antigen Region | 24-52 aa |
Gene ID | 83442 |
---|---|
Other Names | SH3 domain-binding glutamic acid-rich-like protein 3, SH3 domain-binding protein 1, SH3BP-1, SH3BGRL3 |
Target/Specificity | This SH3BGRL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the Central region of human SH3BGRL3. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SH3BGRL3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SH3BGRL3 |
---|---|
Function | Could act as a modulator of glutaredoxin biological activity (Probable). May play a role in cytoskeleton organization (PubMed:34380438). |
Cellular Location | Cytoplasm, cytosol. Cell projection, ruffle membrane. Nucleus |
Tissue Location | Ubiquitous (PubMed:11444877, PubMed:11404387). Expressed in heart, kidney and liver (at protein level) (PubMed:11404387). Expressed in brain, lung, spleen and skeletal muscle (PubMed:11404387). |
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Provided below are standard protocols that you may find useful for product applications.
Background
SH3BGRL3 could act as a modulator of glutaredoxin biological activity.
References
Mazzocco,M., et.al., Biochem. Biophys. Res. Commun. 285 (2), 540-545 (2001)
Henn,A.D., et.al., FASEB J. 15 (7), 1315-1317 (2001)
Seo,J., et.al., Mol. Cells 10 (6), 733-739 (2000)
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