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HDLBP Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - HDLBP Antibody (Center) AP9415c
    Western blot analysis of HDLBP Antibody (Center) (Cat. #AP9415c) in A2058, T47D cell line lysates (35ug/lane). HDLBP (arrow) was detected using the purified Pab.
    detail
  • IHC-P - HDLBP Antibody (Center) AP9415c
    Formalin-fixed and paraffin-embedded human lung carcinoma reacted with HDLBP Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q00341
Other Accession Q9Z1A6, Q8VDJ3
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 141440 Da
Antigen Region 764-791 aa
Additional Information
Gene ID 3069
Other Names Vigilin, High density lipoprotein-binding protein, HDL-binding protein, HDLBP, HBP, VGL
Target/Specificity This HDLBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 764-791 amino acids from the Central region of human HDLBP.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHDLBP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HDLBP
Synonyms HBP, VGL
Function Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.
Cellular Location Cytoplasm. Nucleus
Research Areas
Citations (0)
citation

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Background

High density lipoprotein-binding protein, also known as vigilin, is a 110-kD protein that specifically binds HDL molecules and may function in the removal of excess cellular cholesterol.

References

Chen, S.N., et al. BMC Med. Genet. 10, 111 (2009)
Zhou, J., et al. RNA 14(9):1773-1781(2008)
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)

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$ 182.50
$ 70.00
Cat# AP9415c
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