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SERPINA9 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, FC, E |
|---|---|
| Primary Accession | Q86WD7 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 46557 Da |
| Antigen Region | 194-222 aa |
| Gene ID | 327657 |
|---|---|
| Other Names | Serpin A9, Centerin, Germinal center B-cell-expressed transcript 1 protein, SERPINA9, GCET1, SERPINA11 |
| Target/Specificity | This SERPINA9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-222 amino acids from the Central region of human SERPINA9. |
| Dilution | IHC-P~~1:10~50 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SERPINA9 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SERPINA9 |
|---|---|
| Synonyms | GCET1, SERPINA11 |
| Function | Protease inhibitor that inhibits trypsin and trypsin-like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro). |
| Cellular Location | [Isoform 1]: Secreted. [Isoform 3]: Cytoplasm. [Isoform 5]: Cytoplasm. [Isoform 7]: Membrane; Single-pass type II membrane protein |
| Tissue Location | Highly expressed in normal germinal center (GC) B- cells and GC B-cell-derived malignancies. |
Provided below are standard protocols that you may find useful for product applications.
Background
SERPINA9 is a protease inhibitor that inhibits trypsin and trypsin-like serine proteases (in vitro). This protein inhibits plasmin and thrombin with lower efficiency (in vitro).
References
Luke, M.M., et al. Stroke 40(2):363-368(2009) Paterson, M.A., et al. Am. J. Clin. Pathol. 130(1):117-126(2008) Montes-Moreno, S., et al. Blood 111(1):351-358(2008) Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008) Morrison, A.C., et al. Cerebrovasc. Dis. 26(4):420-424(2008)
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