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GGCT Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GGCT Antibody (C-term) AP9676b
    Western blot analysis of GGCT Antibody (C-term) (Cat. #AP9676b) in 293 cell line lysates (35ug/lane). GGCT (arrow) was detected using the purified Pab.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O75223
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 21008 Da
Antigen Region 139-168 aa
Additional Information
Gene ID 79017
Other Names Gamma-glutamylcyclotransferase, Cytochrome c-releasing factor 21, GGCT, C7orf24, CRF21
Target/Specificity This GGCT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-168 amino acids from the C-terminal region of human GGCT.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGGCT Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GGCT (HGNC:21705)
Synonyms C7orf24, CRF21
Function Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis (PubMed:18515354). Induces release of cytochrome c from mitochondria with resultant induction of apoptosis (PubMed:16765912).
Research Areas
Citations (0)
citation

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Background

GGCT (EC 2.3.2.4) catalyzes the formation of 5-oxoproline (pyroglutamic acid) from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis.

References

Oakley, A.J., et al. J. Biol. Chem. 283(32):22031-22042(2008)
Bae, E., et al. Proteins 70(2):588-591(2008)
Masuda, Y., et al. Biochem. Biophys. Res. Commun. 346(2):454-460(2006)

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$ 365.00
$ 140.00
Cat# AP9676b
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