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ZCRB1 Antibody

     
  • WB - ZCRB1 Antibody ASC10926
    Western blot analysis of ZCRB1 in Raji cell lysate with ZCRB1 antibody at (A) 1 and (B) 2 µg/mL.
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  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8TBF4
Other Accession NP_149105, 51243065
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 24592 Da
Application Notes ZCRB1 antibody can be used for detection of ZCRB1 by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 85437
Target/Specificity ZCRB1;
Reconstitution & Storage ZCRB1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsZCRB1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZCRB1
Cellular Location Nucleus, nucleoplasm
Research Areas
Citations (0)
citation

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Background

ZCRB1 Antibody: ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression is increased following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zing finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. ZCRB1 was identified as one of the protein components of U11/U12 snRNPs, which are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.

References

Wang H, Gao MX, Li L, et al. Isolation, expression, and characterization of the human ZCRB1 gene mapped to 12q2. Genomics2007; 89:59-69.
Trivedi AK, Bararia D, Christopeit M, et al. Proteomic identification of C/EBP-DBD multiprotein complex: JNK1 activates stem cell regulator C/EBPalpha by inhibiting its ubiquitination. Oncogene2007; 1789-801.
Will CL, Schneider C, Hossbach M, et al. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. RNA2004; 10:929-41.

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$ 379.00
Cat# ASC10926
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