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SOCS5 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant SOCS5.

     
  • WB - SOCS5 Antibody (monoclonal) (M01) AT3990a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.73 KDa) .
    detail
  • WB - SOCS5 Antibody (monoclonal) (M01) AT3990a
    SOCS5 monoclonal antibody (M01), clone 2D1 Western Blot analysis of SOCS5 expression in HepG2 ( (Cat # AT3990a )
    detail
  • IHC - SOCS5 Antibody (monoclonal) (M01) AT3990a
    Immunoperoxidase of monoclonal antibody to SOCS5 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
    detail
  • E - SOCS5 Antibody (monoclonal) (M01) AT3990a
    Detection limit for recombinant GST tagged SOCS5 is approximately 0.03ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession O75159
Other Accession BC032862
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2D1
Calculated MW 61246 Da
Additional Information
Gene ID 9655
Other Names Suppressor of cytokine signaling 5, SOCS-5, Cytokine-inducible SH2 protein 6, CIS-6, Cytokine-inducible SH2-containing protein 5, SOCS5, CIS6, CISH5, CISH6, KIAA0671
Target/Specificity SOCS5 (AAH32862, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSOCS5 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
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Background

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

References

The control of allergic conjunctivitis by suppressor of cytokine signaling (SOCS)3 and SOCS5 in a murine model. Ozaki A, et al. J Immunol, 2005 Oct 15. PMID 16210657.Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling. Nicholson SE, et al. Proc Natl Acad Sci U S A, 2005 Feb 15. PMID 15695332.Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling. Kario E, et al. J Biol Chem, 2005 Feb 25. PMID 15590694.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Identification of NPM-ALK interacting proteins by tandem mass spectrometry. Crockett DK, et al. Oncogene, 2004 Apr 8. PMID 14968112.

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$ 350.00
Cat# AT3990a
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