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SLC25A15 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9Y619
Clone Names 101008301
Peptide ID 101008301
Additional Information
Gene ID 10166
Other Names Mitochondrial ornithine transporter 1, Solute carrier family 25 member 15, SLC25A15, ORNT1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC25A15
Synonyms ORC1 {ECO:0000303|PubMed:12807890}, ORNT
Function Ornithine-citrulline antiporter. Connects the cytosolic and the intramitochondrial reactions of the urea cycle by exchanging cytosolic ornithine with matrix citrulline (PubMed:12807890). The stoichiometry is close to 1:1 (By similarity).
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:A0A0G2K309}
Tissue Location Highly expressed in liver, pancreas, testis, lung and small intestine. Lower levels are detected in spleen, kidney, brain and heart.
Research Areas
Citations (0)

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This gene is a member of the mitochondrial carrier family.The encoded protein transports ornithine across the innermitochondrial membrane from the cytosol to the mitochondrialmatrix. The protein is an essential component of the urea cycle,and functions in ammonium detoxification and biosynthesis of theamino acid arginine. Mutations in this gene result inhyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome.There is a pseudogene of this locus on the Y chromosome.


Sokoro, A.A., et al. J. Inherit. Metab. Dis. (2010) In press :Tessa, A., et al. Hum. Mutat. 30(5):741-748(2009)Debray, F.G., et al. J. Med. Genet. 45(11):759-764(2008)Al-Hassnan, Z.N., et al. J. Neurol. Sci. 264 (1-2), 187-194 (2008) :Torisu, H., et al. Brain Dev. 28(5):332-335(2006)

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Cat# BP12166c
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