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PRSS7 Antibody (C-term E979) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P98073
Clone Names 4011212
Peptide ID 4011212
Additional Information
Gene ID 5651
Other Names Enteropeptidase, Enterokinase, Serine protease 7, Transmembrane protease serine 15, Enteropeptidase non-catalytic heavy chain, Enteropeptidase catalytic light chain, TMPRSS15, ENTK, PRSS7
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ENTK, PRSS7
Function Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
Cellular Location Membrane; Single-pass type II membrane protein
Tissue Location Intestinal brush border.
Research Areas
Citations (0)

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This gene encodes an enzyme that converts the pancreaticproenzyme trypsinogen to trypsin, which activates other proenzymesincluding chymotrypsinogen and procarboxypeptidases. The precursorprotein is cleaved into two chains that form a heterodimer linkedby a disulfide bond. This protein is a member of the trypsin familyof peptidases. Mutations in this gene cause enterokinasedeficiency, a malabsorption disorder characterized by diarrhea andfailure to thrive.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Nakanishi, J., et al. J. Invest. Dermatol. 130(4):944-952(2010)Vilen, S.T., et al. Exp. Cell Res. 314(4):914-926(2008)Imamura, T., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 285 (6), G1235-G1241 (2003) :Holzinger, A., et al. Am. J. Hum. Genet. 70(1):20-25(2002)

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Cat# BP12255b
Availability: Back Order
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