|Other Names||Tumor necrosis factor ligand superfamily member 4, Glycoprotein Gp34, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, CD252, TNFSF4, TXGP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a cytokine thatbelongs to the tumor necrosis factor (TNF) ligand family. Thiscytokine is a ligand for receptor TNFRSF4/OX4. It is found to beinvolved in T cell antigen-presenting cell (APC) interactions. Insurface Ig- and CD40-stimulated B cells, this cytokine along withCD70 has been shown to provide CD28-independent costimulatorysignals to T cells. This protein and its receptor are reported todirectly mediate adhesion of activated T cells to vascularendothelial cells.
Karulf, M., et al. J. Immunol. 185(8):4856-4862(2010)Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)
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