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GBA3 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9H227
Clone Names 100311238
Peptide ID 100311238
Additional Information
Gene ID 57733
Other Names Cytosolic beta-glucosidase, Cytosolic beta-glucosidase-like protein 1, GBA3, CBG, CBGL1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GBA3
Synonyms CBG, CBGL1
Function Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.
Cellular Location Cytoplasm, cytosol
Tissue Location Present in small intestine (at protein level). Expressed in liver, small intestine, colon, spleen and kidney Down-regulated in renal cell carcinomas and hepatocellular carcinomas.
Research Areas
Citations (0)

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GBA3, or cytosolic beta-glucosidase (EC, is apredominantly liver enzyme that efficiently hydrolyzesbeta-D-glucoside and beta-D-galactoside, but not any knownphysiologic beta-glycoside, suggesting that it may be involved indetoxification of plant glycosides (de Graaf et al., 2001 [PubMed11389701]). GBA3 also has significant neutral glycosylceramidaseactivity (EC, suggesting that it may be involved in anonlysosomal catabolic pathway of glucosylceramide metabolism(Hayashi et al., 2007 [PubMed 17595169]).


Dekker, N., et al. Blood Cells Mol. Dis. (2010) In press :Noguchi, J., et al. Biochem. Biophys. Res. Commun. 374(3):549-552(2008)Hayashi, Y., et al. J. Biol. Chem. 282(42):30889-30900(2007)Tribolo, S., et al. J. Mol. Biol. 370(5):964-975(2007)Beutler, E., et al. J. Lab. Clin. Med. 144(2):65-68(2004)

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Cat# BP12289b
Availability: Back Order
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