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ZNF146 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q15072 |
|---|---|
| Clone Names | 100324084 |
| Gene ID | 7705 |
|---|---|
| Other Names | Zinc finger protein OZF, Only zinc finger protein, Zinc finger protein 146, ZNF146, OZF |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ZNF146 |
|---|---|
| Synonyms | OZF |
| Cellular Location | Nucleus. |
| Tissue Location | Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpressed in 80% of colorectal cancers. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The ZNF146 protein is a 33 kDa Kruppel protein, composed solely of 10 zinc finger motifs. ZNF146 overexpression in tumours may alter the balance between hRap1 and other telomeric proteins; therefore ZNF146 function may be linked to telomere regulation. ZNF146 is strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. ZNF146 is overexpresseed in 80% of colorectal cancers.
References
Antoine, K., et al. J. Cell. Biochem. 95(4):763-768(2005)Antoine, K., et al. Mol. Cell. Biochem. 271 (1-2), 215-223 (2005) :Grimwood, J., et al. Nature 428(6982):529-535(2004)Ferbus, D., et al. J. Pathol. 200(2):177-182(2003)Pibouin, L., et al. Cytogenet. Cell Genet. 92 (1-2), 80-84 (2001) :
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