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DLL3 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NYJ7 |
|---|---|
| Clone Names | 100324194 |
| Gene ID | 10683 |
|---|---|
| Other Names | Delta-like protein 3, Drosophila Delta homolog 3, Delta3, DLL3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DLL3 |
|---|---|
| Function | Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). |
| Cellular Location | Membrane; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the delta protein ligandfamily. This family functions as Notch ligands that arecharacterized by a DSL domain, EGF repeats, and a transmembranedomain. Mutations in this gene cause autosomal recessivespondylocostal dysostosis 1. Two transcript variants encodingdistinct isoforms have been identified for this gene. [provided byRefSeq].
References
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Heuss, S.F., et al. Proc. Natl. Acad. Sci. U.S.A. 105(32):11212-11217(2008)Maisenbacher, M.K., et al. Hum. Genet. 116(5):416-419(2005)Whittock, N.V., et al. Clin. Genet. 66(1):67-72(2004)Bonafe, L., et al. Clin. Genet. 64(1):28-35(2003)
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