MYCBP Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q99417 |
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Clone Names | 101109003 |
Gene ID | 26292 |
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Other Names | C-Myc-binding protein, Associate of Myc 1, AMY-1, MYCBP, AMY1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MYCBP (HGNC:7554) |
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Synonyms | AMY1 |
Function | May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC. |
Cellular Location | Cytoplasm. Nucleus. Mitochondrion. Note=Translocates into the nucleus in the S phase of the cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1 |
Tissue Location | Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung |
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Provided below are standard protocols that you may find useful for product applications.
Background
The MYCBP gene encodes a protein that binds to theN-terminal region of MYC (MIM 190080) and stimulates the activationof E box-dependent transcription by MYC.
References
Xiong, J., et al. Oncogene 29(35):4980-4988(2010)Wang, H.B., et al. J. Gastrointest. Surg. 14(8):1227-1234(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Sedoris, K.C., et al. Biochemistry 46(29):8659-8668(2007)Ishizaki, R., et al. Genes Cells 11(8):949-959(2006)
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