|Other Names||C-Myc-binding protein, Associate of Myc 1, AMY-1, MYCBP, AMY1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.|
|Cellular Location||Cytoplasm. Nucleus. Mitochondrion. Note=Translocates into the nucleus in the S phase of the cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1|
|Tissue Location||Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung|
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Provided below are standard protocols that you may find useful for product applications.
The MYCBP gene encodes a protein that binds to theN-terminal region of MYC (MIM 190080) and stimulates the activationof E box-dependent transcription by MYC.
Xiong, J., et al. Oncogene 29(35):4980-4988(2010)Wang, H.B., et al. J. Gastrointest. Surg. 14(8):1227-1234(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Sedoris, K.C., et al. Biochemistry 46(29):8659-8668(2007)Ishizaki, R., et al. Genes Cells 11(8):949-959(2006)
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