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SPATA7 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9P0W8 |
|---|---|
| Clone Names | 91102291 |
| Gene ID | 55812 |
|---|---|
| Other Names | Spermatogenesis-associated protein 7, HSD-31, Spermatogenesis-associated protein HSD3, SPATA7, HSD3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SPATA7 |
|---|---|
| Synonyms | HSD3 |
| Function | Involved in the maintenance of both rod and cone photoreceptor cells (By similarity). It is required for recruitment and proper localization of RPGRIP1 to the photoreceptor connecting cilium (CC), as well as photoreceptor-specific localization of proximal CC proteins at the distal CC (By similarity). Maintenance of protein localization at the photoreceptor-specific distal CC is essential for normal microtubule stability and to prevent photoreceptor degeneration (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:Q80VP2}. Note=Localizes to the microtubule network. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene, originally isolated from testis, is alsoexpressed in retina. Mutations in this gene are associated withLeber congenital amaurosis and juvenile retinitis pigmentosa.Alternatively spliced transcript variants encoding differentisoforms have been found for this gene.
References
Perrault, I., et al. Hum. Mutat. 31 (3), E1241-E1250 (2010) :Wang, H., et al. Am. J. Hum. Genet. 84(3):380-387(2009)Zhang, X., et al. J. Mol. Med. 81(6):380-387(2003)Heilig, R., et al. Nature 421(6923):601-607(2003)
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