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EMAL3 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q32P44 |
|---|---|
| Clone Names | 91113297 |
| Gene ID | 256364 |
|---|---|
| Other Names | Echinoderm microtubule-associated protein-like 3, EMAP-3, EML3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | EML3 |
|---|---|
| Function | Regulates mitotic spindle assembly, microtubule (MT)- kinetochore attachment and chromosome separation via recruitment of HAUS augmin-like complex and TUBG1 to the existing MTs and promoting MT-based MT nucleation (PubMed:30723163). Required for proper alignnment of chromosomes during metaphase (PubMed:18445686). |
| Cellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:18445686, ECO:0000305}. Cytoplasm. Nucleus Midbody. Cytoplasm, cytoskeleton, spindle Note=Localizes to microtubules throughout all mitotic stages and localizes to the midbody during cytokinesis |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
EMAL3 may modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity).
References
Tegha-Dunghu, J., et al. J. Cell. Sci. 121 (PT 10), 1718-1726 (2008) :Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Jin, J., et al. Curr. Biol. 14(16):1436-1450(2004)O'Connor, V., et al. Gene 336(1):127-137(2004)Pozuelo Rubio, M., et al. Biochem. J. 379 (PT 2), 395-408 (2004) :
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