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DCUN1D5 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9BTE7
Other Accession NP_115675.1
Clone Names 91218131
Additional Information
Gene ID 84259
Other Names DCN1-like protein 5, DCUN1 domain-containing protein 5, Defective in cullin neddylation protein 1-like protein 5, DCUN1D5
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCUN1D5 (HGNC:28409)
Function Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs) (PubMed:26906416, PubMed:23201271, PubMed:19617556). May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth (PubMed:23098533, PubMed:24192928).
Cellular Location Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Subcellular localization is independent of the interaction with cullins
Tissue Location Weakly expressed in testis, skin and immune tissues (thymus, spleen and lymph nodes).
Research Areas
Citations (0)
citation

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References

Kurz, T., et al. Nature 435(7046):1257-1261(2005)

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$ 277.78
Cat# BP12425b
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