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PDC Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P20941
Clone Names 100318138
Peptide ID 100318138
Additional Information
Gene ID 5132
Other Names Phosducin, PHD, 33 kDa phototransducing protein, Protein MEKA, PDC
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDC
Function May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX.
Cellular Location Cytoplasm, cytosol. Nucleus. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:P19632} Photoreceptor inner segment {ECO:0000250|UniProtKB:P19632}
Research Areas
Citations (0)

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This gene encodes a phosphoprotein, which is located inthe outer and inner segments of the rod cells in the retina. Thisprotein may participate in the regulation of visualphototransduction or in the integration of photoreceptormetabolism. It modulates the phototransduction cascade byinteracting with the beta and gamma subunits of the retinalG-protein transducin. This gene is a potential candidate gene forretinitis pigmentosa and Usher syndrome type II. Alternativelyspliced transcript variants encoding different isoforms have beenidentified.


Beetz, N., et al. J. Clin. Invest. 119(12):3597-3612(2009)Klenk, C., et al. J. Biol. Chem. 281(13):8357-8364(2006)Nishiguchi, K.M., et al. Mol. Vis. 10, 62-64 (2004) :Margulis, A., et al. Mol. Vis. 8, 477-482 (2002) :Wistow, G., et al. Mol. Vis. 8, 196-204 (2002) :

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Cat# BP12439c
Availability: Back Order
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