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RASAL1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O95294
Clone Names 101109067
Peptide ID 101109067
Additional Information
Gene ID 8437
Other Names RasGAP-activating-like protein 1, RASAL1, RASAL
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RASAL1 (HGNC:9873)
Function Probable inhibitory regulator of the Ras-cyclic AMP pathway (PubMed:9751798). Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Tissue Location Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea (PubMed:9751798). Expressed in melanocytes (PubMed:23999003)
Research Areas
Citations (0)

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The protein encoded by this gene is member of the GAP1family of GTPase-activating proteins. These proteins stimulate theGTPase activity of normal RAS p21 but not its oncogeniccounterpart. Acting as a suppressor of RAS function, the proteinenhances the weak intrinsic GTPase activity of RAS proteinsresulting in the inactive GDP-bound form of RAS, thereby allowingcontrol of cellular proliferation and differentiation. Thisparticular family member contains domains which are characteristicof the GAP1 subfamily of RasGAP proteins but, in contrast to theother GAP1 family members, this protein is strongly and selectivelyexpressed in endocrine tissues. Alternatively spliced transcriptvariants that encode different isoforms have been described


Ohta, M., et al. Gastroenterology 136(1):206-216(2009)Jin, H., et al. Proc. Natl. Acad. Sci. U.S.A. 104(30):12353-12358(2007)Liu, Q., et al. J. Cell Biol. 170(2):183-190(2005)Schmitt, J.M., et al. J. Biol. Chem. 277(45):43024-43032(2002)Allen, M., et al. Gene 218 (1-2), 17-25 (1998) :

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Cat# BP12460c
Availability: Back Order
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