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WFDC1 Antibody (C-term H163) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9HC57
Clone Names 80924278
Peptide ID 80924278
Additional Information
Gene ID 58189
Other Names WAP four-disulfide core domain protein 1, Prostate stromal protein ps20, ps20 growth inhibitor, WFDC1, PS20
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name WFDC1
Synonyms PS20
Function Has growth inhibitory activity.
Cellular Location Secreted.
Research Areas
Citations (0)

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This gene encodes a member of the WAP-type four disulfidecore domain family. The WAP-type four-disulfide core domain, or WAPsignature motif, contains eight cysteines forming four disulfidebonds at the core of the protein, and functions as a proteaseinhibitor in many family members. The encoded protein shares 81%amino acid identity with the rat ps20 protein, which was originallyidentified as a secreted growth inhibitor. This gene is mapped tochromosome 16q24, an area of frequent loss of heterozygosity incancers, including prostate, breast and hepatocellular cancers andWilms' tumor. Owing to its location and a possible growthinhibitory property of its gene product, this gene is suggested tobe a tumor suppressor gene.


Briggs, F.B., et al. Genes Immun. 11(3):199-208(2010)Madar, S., et al. Carcinogenesis 30(1):20-27(2009)Liu, S., et al. Clin. Exp. Metastasis 26(7):739-749(2009)Alvarez, R., et al. J. Virol. 82(1):471-486(2008)Watson, J.E., et al. Prostate 61(2):192-199(2004)

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Cat# BP12472b
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