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SOX15 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O60248
Clone Names 81201135
Peptide ID 81201135
Additional Information
Other Names Protein SOX-15, Protein SOX-12, Protein SOX-20, SOX15, SOX12, SOX20, SOX26, SOX27
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX15
Synonyms SOX12, SOX20, SOX26, SOX27
Function Binds to the 5'-AACAAT-3' sequence.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}
Tissue Location Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis. EMBL; AB006867; BAA25663.1; -; mRNA EMBL; AK301687; BAG63159.1; -; mRNA EMBL; AC016876; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; CH471108; EAW90156.1; -; Genomic_DNA EMBL; CH471108; EAW90157.1; -; Genomic_DNA EMBL; BC000985; AAH00985.1; -; mRNA EMBL; BC072003; AAH72003.1; -; mRNA EMBL; X73039; CAA51520.1; -; Genomic_DNA EMBL; AJ006222; CAA06920.1; -; mRNA EMBL; AB025355; BAA78784.1; -; Genomic_DNA CCDS; CCDS32549.1; -. [O60248-1] PIR; S34119; S34119 RefSeq; NP_008873.1; NM_006942.1. [O60248-1] UniGene; Hs.95582; - ProteinModelPortal; O60248; - SMR; O60248; - BioGrid; 112548; 3 IntAct; O60248; 2 STRING; 9606.ENSP00000355354; - iPTMnet; O60248; - PhosphoSitePlus; O60248; - BioMuta; SOX15; - EPD; O60248; - jPOST; O60248; - MaxQB; O60248; - PaxDb; O60248; - PeptideAtlas; O60248; - PRIDE; O60248; - ProteomicsDB; 49282; - DNASU; 6665; - Ensembl; ENST00000250055; ENSP00000355354; ENSG00000129194. [O60248-1] Ensembl; ENST00000538513; ENSP00000439311; ENSG00000129194. [O60248-1] Ensembl; ENST00000570788; ENSP00000458286; ENSG00000129194. [O60248-2] GeneID; 6665; - KEGG; hsa:6665; - UCSC; uc002ghy.2; human. [O60248-1] CTD; 6665; - DisGeNET; 6665; - EuPathDB; HostDB:ENSG00000129194.7; - GeneCards; SOX15; - HGNC; HGNC:11196; SOX15 HPA; HPA067196; - HPA; HPA074049; - MIM; 601297; gene neXtProt; NX_O60248; - OpenTargets; ENSG00000129194; - PharmGKB; PA36033; - eggNOG; KOG0527; Eukaryota eggNOG; ENOG410XT0K; LUCA GeneTree; ENSGT00940000162099; - HOGENOM; HOG000231647; - HOVERGEN; HBG055512; - InParanoid; O60248; - KO; K09271; - OMA; YGSSHCK; - OrthoDB; 369754at2759; - PhylomeDB; O60248; - TreeFam; TF351735; - GeneWiki; SOX15; - GenomeRNAi; 6665; - PRO; PR:O60248; - Proteomes; UP000005640; Chromosome 17 Bgee; ENSG00000129194; Expressed in 173 organ(s), highest expression level in lower esophagus mucosa Genevisible; O60248; HS GO; GO:0005737; C:cytoplasm; IEA:Ensembl GO; GO:0044798; C:nuclear transcription factor complex; IBA:GO_Central GO; GO:0005634; C:nucleus; IBA:GO_Central GO; GO:0003682; F:chromatin binding; IEA:Ensembl GO; GO:0003677; F:DNA binding; NAS:UniProtKB GO; GO:0003700; F:DNA-binding transcription factor activity; NAS:UniProtKB GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; ISA:NTNU_SB GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl GO; GO:0030154; P:cell differentiation; ISS:BHF-UCL GO; GO:0007417; P:central nervous system development; IBA:GO_Central GO; GO:0006325; P:chromatin organization; NAS:UniProtKB GO; GO:0008584; P:male gonad development; TAS:ProtInc GO; GO:0048627; P:myoblast development; ISS:BHF-UCL GO; GO:0045843; P:negative regulation of striated muscle tissue development; ISS:BHF-UCL GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; ISS:BHF-UCL GO; GO:0030182; P:neuron differentiation; IBA:GO_Central GO; GO:0070318; P:positive regulation of G0 to G1 transition; ISS:BHF-UCL GO; GO:2000288; P:positive regulation of myoblast proliferation; ISS:BHF-UCL GO; GO:0014718; P:positive regulation of satellite cell activation involved in skeletal muscle regeneration; ISS:BHF-UCL GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; ISS:BHF-UCL GO; GO:0006357; P:regulation of transcription by RNA polymerase II; TAS:ProtInc GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central GO; GO:0043403; P:skeletal muscle tissue regeneration; IEA:Ensembl Gene3D;; -; 1 InterPro; IPR009071; HMG_box_dom InterPro; IPR036910; HMG_box_dom_sf InterPro; IPR031269; SOX15 PANTHER; PTHR10270:SF45; PTHR10270:SF45; 1 Pfam; PF00505; HMG_box; 1 SMART; SM00398; HMG; 1 SUPFAM; SSF47095; SSF47095; 1 PROSITE; PS50118; HMG_BOX_2; 1 1: Evidence at protein level; Alternative splicing; Complete proteome; DNA-binding; Nucleus; Phosphoprotein; Reference proteome CHAIN 1 233 Protein SOX-15 /FTId=PRO_0000048762 DNA_BIND 49 117 HMG box. {ECO:0000255|PROSITE- ProRule:PRU00267} MOD_RES 37 37 Phosphoserine VAR_SEQ 179 233 Missing (in isoform 2) /FTId=VSP_056668 CONFLICT 25 27 SSS -> AAA (in Ref. 6). CONFLICT 69 70 QQ -> HE (in Ref. 7; CAA51520) CONFLICT 191 191 S -> F (in Ref. 9; BAA78784) CONFLICT 216 218 PTP -> STS (in Ref. 9; BAA78784) CONFLICT 225 226 GA -> VP (in Ref. 9; BAA78784) SEQUENCE 233 AA; 25251 MW; 6B52AE455C7C8CCE CRC64; MALPGSSQDQ AWSLEPPAAT AAASSSSGPQ EREGAGSPAA PGTLPLEKVK RPMNAFMVWS SAQRRQMAQQ NPKMHNSEIS KRLGAQWKLL DEDEKRPFVE EAKRLRARHL RDYPDYKYRP RRKAKSSGAG PSRCGQGRGN LASGGPLWGP GYATTQPSRG FGYRPPSYST AYLPGSYGSS HCKLEAPSPC SLPQSDPRLQ GELLPTYTHY LPPGSPTPYN PPLAGAPMPL THL
Research Areas
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This gene encodes a member of the SOX (SRY-relatedHMG-box) family of transcription factors involved in the regulationof embryonic development and in the determination of the cell fate.The encoded protein may act as a transcriptional regulator afterforming a protein complex with other proteins. [provided byRefSeq].


Sakai, N., et al. J. Endocrinol. 198(3):489-497(2008)Yan, H.T., et al. Mol. Cells 24(3):323-328(2007)Schepers, G.E., et al. Dev. Cell 3(2):167-170(2002)Wilson, M., et al. Curr. Opin. Genet. Dev. 12(4):441-446(2002)Miyashita, A., et al. Gene 237(1):53-60(1999)

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