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NXN Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6DKJ4
Clone Names 91119224
Additional Information
Gene ID 64359
Other Names Nucleoredoxin, NXN, NRX
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NXN
Synonyms NRX
Function Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity).
Cellular Location Cytoplasm, cytosol {ECO:0000250|UniProtKB:P97346}. Nucleus {ECO:0000250|UniProtKB:P97346}
Research Areas
Citations (0)
citation

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Background

NXN functions as a redox-dependent negative regulator of the Wnt signaling pathway. May function as a transcriptional regulator. May regulate phosphatase 2A (By similarity).

References

Ollila, H.M., et al. Mol. Psychiatry 14(4):351-353(2009)Funato, Y., et al. Antioxid. Redox Signal. 9(8):1035-1057(2007)Hirota, K., et al. Biochem. Biophys. Res. Commun. 274(1):177-182(2000)Kurooka, H., et al. Genomics 39(3):331-339(1997)

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$ 277.78
Cat# BP12483c
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