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RENBP Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P51606 |
|---|---|
| Clone Names | 100318177 |
| Gene ID | 5973 |
|---|---|
| Other Names | N-acylglucosamine 2-epimerase, AGE, GlcNAc 2-epimerase, N-acetyl-D-glucosamine 2-epimerase, Renin-binding protein, RnBP, RENBP |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RENBP |
|---|---|
| Function | Catalyzes the interconversion of N-acetylglucosamine to N- acetylmannosamine (PubMed:9990133, PubMed:10502668, PubMed:12499362). Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (PubMed:9990133). |
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Provided below are standard protocols that you may find useful for product applications.
Background
The gene product inhibits renin activity by forming adimer with renin, a complex known as high molecular weight renin.The encoded protein contains a leucine zipper domain, which isessential for its dimerization with renin. The gene product cancatalyze the interconversion of N-acetylglucosamine toN-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase.Transcript variants utilizing alternative promoters have beendescribed in the literature.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Gu, D., et al. J. Hypertens. 28(6):1210-1220(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Luchansky, S.J., et al. J. Biol. Chem. 278(10):8035-8042(2003)Bohlmeyer, T., et al. J. Card. Fail. 9(1):59-68(2003)
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