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GPD2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P43304 |
|---|---|
| Clone Names | 100318204 |
| Gene ID | 2820 |
|---|---|
| Other Names | Glycerol-3-phosphate dehydrogenase, mitochondrial, GPD-M, GPDH-M, mtGPD, GPD2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GPD2 (HGNC:4456) |
|---|---|
| Function | Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta- cell glucose-sensing device. |
| Cellular Location | Mitochondrion. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene localizes to the innermitochondrial membrane and catalyzes the conversion ofglycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as acofactor. Along with GDP1, the encoded protein constitutes theglycerol phosphate shuttle, which reoxidizes NADH formed duringglycolysis. Two transcript variants encoding the same protein havebeen found for this gene.
References
Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)Daoud, H., et al. Hum. Genet. 124(6):649-658(2009)Chowdhury, S.K., et al. Free Radic. Res. 41(10):1116-1124(2007)Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
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