HOXB3 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P14651 |
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Clone Names | 100318211 |
Gene ID | 3213 |
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Other Names | Homeobox protein Hox-B3, Homeobox protein Hox-27, Homeobox protein Hox-2G, HOXB3, HOX2G |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | HOXB3 |
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Synonyms | HOX2G |
Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the Antp homeobox family andencodes a nuclear protein with a homeobox DNA-binding domain. It isincluded in a cluster of homeobox B genes located on chromosome 17.The encoded protein functions as a sequence-specific transcriptionfactor that is involved in development. Increased expression ofthis gene is associated with a distinct biologic subset of acutemyeloid leukemia (AML).
References
Palakurthy, R.K., et al. Mol. Cell 36(2):219-230(2009)Ferrai, C., et al. Mol. Biol. Cell 20(15):3543-3551(2009)Chung, N., et al. Mol. Biol. Rep. 36(2):227-235(2009)Speleman, F., et al. Leukemia 19(3):358-366(2005)Roche, J., et al. Leukemia 18(6):1059-1063(2004)
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