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MLPH Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9BV36
Clone Names 100318125
Peptide ID 100318125
Additional Information
Gene ID 79083
Other Names Melanophilin, Exophilin-3, Slp homolog lacking C2 domains a, SlaC2-a, Synaptotagmin-like protein 2a, MLPH, SLAC2A
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SLAC2A
Function Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor protein MYO5A.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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This gene encodes a member of the exophilin subfamily ofRab effector proteins. The protein forms a ternary complex with thesmall Ras-related GTPase Rab27A in its GTP-bound form and the motorprotein myosin Va. A similar protein complex in mouse functions totether pigment-producing organelles called melanosomes to the actincytoskeleton in melanocytes, and is required for visiblepigmentation in the hair and skin. A mutation in this gene resultsin Griscelli syndrome type 3, which is characterized by asilver-gray hair color and abnormal pigment distribution in thehair shaft. Several alternatively spliced transcript variants ofthis gene have been described, but the full-length nature of someof these variants has not been determined.


Park, J.W., et al. J. Med. Genet. 43(7):598-608(2006)Seabra, M.C., et al. Traffic 5(6):393-399(2004)Fukuda, M., et al. J. Cell. Sci. 117 (PT 4), 583-591 (2004) :Lukusa, T., et al. Genet. Couns. 15(3):293-301(2004)Menasche, G., et al. J. Clin. Invest. 112(3):450-456(2003)

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Cat# BP12611b
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