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SQLE Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q14534
Clone Names 100324049
Additional Information
Gene ID 6713
Other Names Squalene monooxygenase, Squalene epoxidase, SE, SQLE, ERG1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SQLE
Synonyms ERG1
Function Catalyzes the stereospecific oxidation of squalene to (S)- 2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
Cellular Location Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein
Tissue Location Detected in liver (at protein level).
Research Areas
Citations (0)
citation

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Background

Squalene epoxidase catalyzes the first oxygenation step insterol biosynthesis and is thought to be one of the rate-limitingenzymes in this pathway.

References

Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)Helms, M.W., et al. Br. J. Cancer 99(5):774-780(2008)Liu, Y., et al. Lung Cancer 56(3):307-317(2007)

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$ 277.78
Cat# BP12624a
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