Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
CEBPD Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P49716 |
|---|---|
| Clone Names | 80924125 |
| Gene ID | 1052 |
|---|---|
| Other Names | CCAAT/enhancer-binding protein delta, C/EBP delta, Nuclear factor NF-IL6-beta, NF-IL6-beta, CEBPD |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CEBPD |
|---|---|
| Function | Transcription activator that recognizes two different DNA motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers (PubMed:16397300). Important transcription factor regulating the expression of genes involved in immune and inflammatory responses (PubMed:1741402, PubMed:16397300). Transcriptional activator that enhances IL6 transcription alone and as heterodimer with CEBPB (PubMed:1741402). |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this intronless gene is a bZIPtranscription factor which can bind as a homodimer to certain DNAregulatory regions. It can also form heterodimers with the relatedprotein CEBP-alpha. The encoded protein is important in theregulation of genes involved in immune and inflammatory responses,and may be involved in the regulation of genes associated withactivation and/or differentiation of macrophages. The cytogeneticlocation of this locus has been reported as both 8p11 and 8q11.
References
Zannetti, C., et al. J. Biol. Chem. 285(45):34773-34780(2010)Wang, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(37):16131-16136(2010)Hour, T.C., et al. Biochem. Pharmacol. 80(3):325-334(2010)Bennett, C.E., et al. Diab Vasc Dis Res 7(3):195-203(2010)Payne, V.A., et al. Biochem. J. 425(1):215-223(2010)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
