|Other Names||Sodium/hydrogen exchanger 2, Na(+)/H(+) exchanger 2, NHE-2, Solute carrier family 9 member 2, SLC9A2, NHE2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine|
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Provided below are standard protocols that you may find useful for product applications.
SLC9A2 is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Son, E.J., et al. J. Cell. Biochem. 107(5):965-972(2009)Joly, F., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 297 (1), G116-G123 (2009) :Musch, M.W., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 296 (2), G202-G210 (2009) :Beltran, A.R., et al. Pflugers Arch. 455(5):799-810(2008)
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