ONECUT1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UBC0 |
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Clone Names | 100318258 |
Gene ID | 3175 |
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Other Names | Hepatocyte nuclear factor 6, HNF-6, One cut domain family member 1, One cut homeobox 1, ONECUT1, HNF6, HNF6A |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ONECUT1 |
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Synonyms | HNF6, HNF6A |
Function | Transcriptional activator. Binds the consensus sequence 5'- DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription. |
Cellular Location | Nucleus. |
Tissue Location | Highly expressed in liver; lower expression in testis and skin |
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Provided below are standard protocols that you may find useful for product applications.
Background
ONECUT1 is a transcriptional activator. It binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
References
Lee, Y.S., et al. Biochem. J. 413(3):559-569(2008)Jiang, X., et al. Oncol. Rep. 19(1):157-163(2008)Lehner, F., et al. FASEB J. 21(7):1445-1462(2007)Rausa, F.M. III, et al. J. Biol. Chem. 279(41):43070-43076(2004)Thomas, H., et al. Nucleic Acids Res. 32 (19), E150 (2004) :
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