|Other Names||Multivesicular body subunit 12B, ESCRT-I complex subunit MVB12B, Protein FAM125B, MVB12B, C9orf28, FAM125B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.|
|Cellular Location||Endosome. Late endosome membrane; Peripheral membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. FAM125B is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.
Tsunematsu, T., et al. Biochem. Biophys. Res. Commun. 399(2):232-237(2010)Letra, A., et al. Am. J. Med. Genet. A 152A (7), 1701-1710 (2010) :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :McClay, J.L., et al. Mol. Psychiatry (2009) In press :Morita, E., et al. Cell Host Microbe 2(1):41-53(2007)
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