NKX2-2 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O95096 |
---|---|
Clone Names | 100324114 |
Gene ID | 4821 |
---|---|
Other Names | Homeobox protein Nkx-22, Homeobox protein NK-2 homolog B, NKX2-2, NKX22, NKX2B |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | NKX2-2 |
---|---|
Synonyms | NKX2.2, NKX2B |
Function | Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene contains a homeoboxdomain and may be involved in the morphogenesis of the centralnervous system. This gene is found on chromosome 20 near NKX2-4,and these two genes appear to be duplicated on chromosome 14 in theform of TITF1 and NKX2-8. The encoded protein is likely to be anuclear transcription factor.
References
Wang, Y.C., et al. J. Surg. Res. 163(1):47-51(2010)Wang, Y.C., et al. Endocr. Relat. Cancer 16(1):267-279(2009)Chen, M., et al. J. Biol. Chem. 284(3):1484-1494(2009)Owen, L.A., et al. PLoS ONE 3 (4), E1965 (2008) :Pauls, S., et al. Dev. Biol. 304(2):875-890(2007)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.