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DRP2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q13474 |
|---|---|
| Clone Names | 100324215 |
| Gene ID | 1821 |
|---|---|
| Other Names | Dystrophin-related protein 2, DRP-2, DRP2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DRP2 |
|---|---|
| Function | Required for normal myelination and for normal organization of the cytoplasm and the formation of Cajal bands in myelinating Schwann cells. Required for normal PRX location at appositions between the abaxonal surface of the myelin sheath and the Schwann cell plasma membrane. Possibly involved in membrane-cytoskeleton interactions of the central nervous system. |
| Cellular Location | Postsynaptic density {ECO:0000250|UniProtKB:Q9EPA0}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9EPA0}. Perikaryon {ECO:0000250|UniProtKB:Q9EPA0}. Cell membrane {ECO:0000250|UniProtKB:Q05AA6}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q05AA6}. Note=Detected in Schwann cells at periaxonal myelin membranes. {ECO:0000250|UniProtKB:Q05AA6} |
| Tissue Location | Detected in fetal brain. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Members of the dystrophin family of proteins perform acritical role in the maintenance of membrane-associated complexesat points of intercellular contact in vertebrate cells. The proteinencoded by this gene is predicted to resemble certain shortC-terminal isoforms of dystrophin and dystrophin-related protein 1(DRP1 or utrophin). DRP2 is expressed principally in the brain andspinal cord. Two transcript variants encoding different isoformshave been found for this gene.
References
Pasalic, D., et al. Mol. Biol. Rep. 36(4):775-780(2009)Sediva, A., et al. J. Clin. Immunol. 27(6):640-646(2007)van Oijen, M., et al. Neurobiol. Aging 28(9):1361-1366(2007)Suk Danik, J., et al. Ann. Hum. Genet. 70 (PT 6), 705-716 (2006) :Ujike, H., et al. Ann. N. Y. Acad. Sci. 1074, 90-96 (2006) :
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