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STARD4 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96DR4
Clone Names 100416038
Additional Information
Gene ID 134429
Other Names StAR-related lipid transfer protein 4, START domain-containing protein 4, StARD4, STARD4
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name STARD4
Function Involved in the intracellular transport of cholesterol. Binds cholesterol or other sterols.
Research Areas
Citations (0)
citation

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Background

Cholesterol homeostasis is regulated, at least in part, bysterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM184756) and by liver X receptors (e.g., LXRA; MIM 602423). Uponsterol depletion, LXRs are inactive and SREBPs are cleaved, afterwhich they bind promoter SREs and activate genes involved incholesterol biosynthesis and uptake. Sterol transport is mediatedby vesicles or by soluble protein carriers, such as steroidogenicacute regulatory protein (STAR; MIM 600617). STAR is homologous toa family of proteins containing a 200- to 210-amino acidSTAR-related lipid transfer (START) domain, including STARD4(Soccio et al., 2002 [PubMed 12011452]).

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Korytowski, W., et al. Biochem. Biophys. Res. Commun. 392(1):58-62(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Rodriguez-Agudo, D., et al. J. Lipid Res. 49(7):1409-1419(2008)

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$ 277.78
Cat# BP12801a
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