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RBM28 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NW13
Clone Names 100324269
Additional Information
Gene ID 55131
Other Names RNA-binding protein 28, RNA-binding motif protein 28, RBM28
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RBM28
Function Nucleolar component of the spliceosomal ribonucleoprotein complexes.
Cellular Location Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:17081119, ECO:0000269|Ref.7}
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a specific nucleolarcomponent of the spliceosomal small nuclear ribonucleoprotein(snRNP)complexes . It specifically associates with U1, U2, U4, U5,and U6 small nuclear RNAs (snRNAs), possibly coordinating theirtransition through the nucleolus. Mutation in this gene causesalopecia, progressive neurological defects, and endocrinopathy (ANEsyndrome), a pleiotropic and clinically heterogeneous disorder.Alternatively spliced transcript variants encoding differentisoforms have been found for this gene.

References

Spiegel, R., et al. Eur. J. Endocrinol. 162(6):1021-1025(2010)Nousbeck, J., et al. Am. J. Hum. Genet. 82(5):1114-1121(2008)Damianov, A., et al. Biol. Chem. 387 (10-11), 1455-1460 (2006) :Andersen, J.S., et al. Nature 433(7021):77-83(2005)Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002)

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$ 277.78
Cat# BP12819a
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