ACOT4 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8N9L9 |
---|---|
Clone Names | 100405168 |
Gene ID | 122970 |
---|---|
Other Names | Acyl-coenzyme A thioesterase 4, Acyl-CoA thioesterase 4, PTE-2b, Peroxisomal acyl coenzyme A thioester hydrolase Ib, Peroxisomal long-chain acyl-CoA thioesterase Ib, PTE-Ib, ACOT4, PTE2B, PTEIB |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ACOT4 |
---|---|
Synonyms | PTE2B, PTEIB |
Function | Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16940157). Functions as a peroxisomal succinyl-coenzyme A thioesterase that can also hydrolyze glutaryl-CoA and long chain saturated acyl-CoAs (PubMed:16940157). |
Cellular Location | Peroxisome. |
Tissue Location | Strongest expression in liver and kidney and weaker expression in placenta, heart, and muscle |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs.
References
Hunt, M.C., et al. FASEB J. 20(11):1855-1864(2006)Westin, M.A., et al. J. Biol. Chem. 280(46):38125-38132(2005)Hunt, M.C., et al. J. Lipid Res. 46(9):2029-2032(2005)Jones, J.M., et al. Biochem. Biophys. Res. Commun. 275(1):233-240(2000)Hunt, M.C., et al. J. Biol. Chem. 274(48):34317-34326(1999)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.