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Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q12926 |
|---|---|
| Clone Names | 91009004 |
| Peptide ID | 91009004 |
| Gene ID | 1993 |
|---|---|
| Other Names | ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, HuB, Nervous system-specific RNA-binding protein Hel-N1, ELAVL2, HUB |
| Format | Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ELAVL2 |
|---|---|
| Synonyms | HUB |
| Function | Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR. |
| Tissue Location | Brain; neural-specific. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a neural-specificRNA-binding protein that is known to bind to several 3' UTRs,including its own and also that of FOS and ID. The encoded proteinmay recognize a GAAA motif in the RNA. Three transcript variantsencoding two different isoforms have been found for this gene.
References
Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009) :D'Alessandro, V., et al. Cell. Oncol. 30(4):291-297(2008)Jonson, L., et al. Mol. Cell Proteomics 6(5):798-811(2007)Yano, M., et al. J. Biol. Chem. 280(13):12690-12699(2005)
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