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SFRP5 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q5T4F7
Clone Names 100324160
Additional Information
Gene ID 6425
Other Names Secreted frizzled-related protein 5, sFRP-5, Frizzled-related protein 1b, FRP-1b, Secreted apoptosis-related protein 3, SARP-3, SFRP5, FRP1B, SARP3
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SFRP5
Synonyms FRP1B, SARP3
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.
Cellular Location Secreted.
Tissue Location Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle
Research Areas
Citations (0)
citation

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Background

Secreted frizzled-related protein 5 (SFRP5) is a member ofthe SFRP family that contains a cysteine-rich domain homologous tothe putative Wnt-binding site of Frizzled proteins. SFRPs act assoluble modulators of Wnt signaling. SFRP5 and SFRP1 may beinvolved in determining the polarity of photoreceptor cells in theretina. SFRP5 is highly expressed in the retinal pigmentepithelium, and moderately expressed in the pancreas. [provided byRefSeq].

References

Su, H.Y., et al. Int. J. Cancer 127(3):555-567(2010)Sharma, S., et al. Am. J. Respir. Crit. Care Med. 181(4):328-336(2010)Jost, E., et al. Cancer Lett. 281(1):24-31(2009)Zhao, C., et al. BMC Cancer 9, 224 (2009) :Tanaka, J., et al. Hepatogastroenterology 55(85):1265-1268(2008)

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$ 277.78
Cat# BP12966c
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