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TAS2R1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NYW7 |
|---|---|
| Clone Names | 100324290 |
| Gene ID | 50834 |
|---|---|
| Other Names | Taste receptor type 2 member 1, T2R1, Taste receptor family B member 7, TRB7, TAS2R1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TAS2R1 |
|---|---|
| Function | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. |
| Cellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Location | Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of a family of candidate tastereceptors that are members of the G protein-coupled receptorsuperfamily and that are specifically expressed by taste receptorcells of the tongue and palate epithelia. This intronless tastereceptor gene encodes a 7-transmembrane receptor protein,functioning as a bitter taste receptor. This gene is mapped tochromosome 5p15, the location of a genetic locus (PROP) thatcontrols the detection of the bitter compound6-n-propyl-2-thiouracil.
References
Upadhyaya, J., et al. Biochem. Biophys. Res. Commun. 398(2):331-335(2010)Weiss, L.A., et al. Nature 461(7265):802-808(2009)Go, Y., et al. Genetics 170(1):313-326(2005)Fischer, A., et al. Mol. Biol. Evol. 22(3):432-436(2005)Zhang, Y., et al. Cell 112(3):293-301(2003)
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